Product Name
MLNR, Blocking Peptide
Product Synonym Names
Motilin receptor; G-protein coupled receptor 38; MLNR; GPR38; MTLR; MTLR1
Product Gene Name
MLNR blocking peptide
[Similar Products]
Product Synonym Gene Name
GPR38; MTLR; MTLR1[Similar Products]
Antibody/Peptide Pairs
MLNR peptide (MBS9219318) is used for blocking the activity of MLNR antibody (MBS9202840)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43193
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cell membrane; Multi-pass membrane protein.
Tissue Location
Expressed only in thyroid, stomach, and bone marrow
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of MLNR blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MLNR blocking peptide
Receptor for motilin.
NCBI/Uniprot data below describe general gene information for MLNR. It may not necessarily be applicable to this product.
NCBI Accession #
O43193.1
[Other Products]
UniProt Primary Accession #
O43193
[Other Products]
UniProt Related Accession #
O43193[Other Products]
Molecular Weight
42,026 Da
NCBI Official Full Name
Motilin receptor
NCBI Official Synonym Full Names
motilin receptor
NCBI Official Symbol
MLNR??[Similar Products]
NCBI Official Synonym Symbols
GPR38; MTLR1
??[Similar Products]
NCBI Protein Information
motilin receptor
UniProt Protein Name
Motilin receptor
UniProt Synonym Protein Names
G-protein coupled receptor 38
Protein Family
Motilin receptor
UniProt Gene Name
MLNR??[Similar Products]
UniProt Synonym Gene Names
GPR38; MTLR; MTLR1??[Similar Products]
UniProt Entry Name
MTLR_HUMAN
NCBI Summary for MLNR
Motilin is a 22 amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract. The protein encoded by this gene is a motilin receptor which is a member of the G-protein coupled receptor 1 family. This member is a multi-pass transmembrane protein, and is an important therapeutic target for the treatment of hypomotility disorders. [provided by RefSeq, Aug 2011]
UniProt Comments for MLNR
MLNR: Receptor for motilin. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q14-q21
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: digestion
Research Articles on MLNR
1. data support important roles of new regions in the TM domains of the motilin receptor for erythromycin action, suggesting differential mechanisms of actions by peptidyl and non-peptidyl ligands
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
