Product Name
GPR38 (MLNR), Polyclonal Antibody
Full Product Name
Anti-GPR38 Antibody
Product Synonym Names
GPR38; MTLR; MTLR1; Motilin receptor; G-protein coupled receptor 38
Product Gene Name
anti-MLNR antibody
[Similar Products]
Antibody/Peptide Pairs
GPR38 peptide (MBS824268) is used for blocking the activity of GPR38 antibody (MBS820139)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43193
Species Reactivity
Human, Mouse
Specificity
Recognizes endogenous levels of GPR38 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GPR38. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-MLNR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MLNR antibody
Rabbit polyclonal antibody to GPR38
Applications Tested/Suitable for anti-MLNR antibody
Western Blot (WB)
Application Notes for anti-MLNR antibody
WB (1/500 - 1/1000)
Western Blot (WB) of anti-MLNR antibody
Western blot analysis of GPR38 expression in HEK293T (A), SP2/0 (B), NIH3T3 (C) whole cell lysates.
NCBI/Uniprot data below describe general gene information for MLNR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001498.1
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NCBI GenBank Nucleotide #
NM_001507.1
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UniProt Primary Accession #
O43193
[Other Products]
UniProt Related Accession #
O43193[Other Products]
Molecular Weight
42,026 Da
NCBI Official Full Name
motilin receptor
NCBI Official Synonym Full Names
motilin receptor
NCBI Official Symbol
MLNR??[Similar Products]
NCBI Official Synonym Symbols
GPR38; MTLR1
??[Similar Products]
NCBI Protein Information
motilin receptor; G protein-coupled receptor 38
UniProt Protein Name
Motilin receptor
UniProt Synonym Protein Names
G-protein coupled receptor 38
Protein Family
Motilin receptor
UniProt Gene Name
MLNR??[Similar Products]
UniProt Synonym Gene Names
GPR38; MTLR; MTLR1??[Similar Products]
UniProt Entry Name
MTLR_HUMAN
NCBI Summary for MLNR
Motilin is a 22 amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract. The protein encoded by this gene is a motilin receptor which is a member of the G-protein coupled receptor 1 family. This member is a multi-pass transmembrane protein, and is an important therapeutic target for the treatment of hypomotility disorders. [provided by RefSeq, Aug 2011]
UniProt Comments for MLNR
MLNR: Receptor for motilin. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q14-q21
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; growth hormone-releasing hormone receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; digestion
Research Articles on MLNR
1. data support important roles of new regions in the TM domains of the motilin receptor for erythromycin action, suggesting differential mechanisms of actions by peptidyl and non-peptidyl ligands
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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