Full Product Name
CD32c Antibody
Product Synonym Names
CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-c; IgG Fc receptor II-c; CDw32; Fc-gamma RII-c; Fc-gamma-RIIc; FcRII-c; CD32
Product Gene Name
anti-CD32c antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P31995
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of CD32c protein.
Purity/Purification
Immunogen affinity chromatography
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/mL (lot specific)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD32c.
Preparation and Storage
Store at -20 degree C.
Other Notes
Small volumes of anti-CD32c antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-CD32c antibody
Total protein Ab
Applications Tested/Suitable for anti-CD32c antibody
Western Blot (WB)
Application Notes for anti-CD32c antibody
WB: 1:500-1:1000
Western Blot (WB) of anti-CD32c antibody
Western blot analysis of ZNF436 expression in HepG2, U251 whole cell lysates.
NCBI/Uniprot data below describe general gene information for CD32c. It may not necessarily be applicable to this product.
NCBI Accession #
NP_963857.3
[Other Products]
NCBI GenBank Nucleotide #
NM_201563.5
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UniProt Primary Accession #
P31995
[Other Products]
UniProt Secondary Accession #
O00523; O00524; O00525[Other Products]
UniProt Related Accession #
P31995[Other Products]
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-c
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIc (gene/pseudogene)
NCBI Official Symbol
FCGR2C??[Similar Products]
NCBI Official Synonym Symbols
CD32; FCG2; CD32C; CDW32; IGFR2; FCRIIC
??[Similar Products]
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-c
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-c
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-c; Fc-gamma-RIIc; FcRII-c; CD_antigen: CD32
UniProt Gene Name
FCGR2C??[Similar Products]
UniProt Synonym Gene Names
CD32; FCG2; IGFR2; IgG Fc receptor II-c; Fc-gamma-RIIc; FcRII-c??[Similar Products]
NCBI Summary for CD32c
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]
UniProt Comments for CD32c
Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.CautionHas sometimes been attributed to correspond to FcR-IIB.
Research Articles on CD32c
1. When higher-affinity genotypes for FCGR2A, FCGR3A, and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 treatment
Precautions
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Disclaimer
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